Dale A Ramsden Selected Research

DNA polymerase mu

5/2008	End-bridging is required for pol mu to efficiently promote repair of noncomplementary ends by nonhomologous end joining.
10/2007	Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining.

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Dale A Ramsden Research Topics

Disease

13	Chromosome Breakage 01/2021 - 09/2004
5	Neoplasms (Cancer) 01/2022 - 12/2012
4	Genomic Instability 01/2022 - 12/2012
1	Genetic Translocation (Chromosomal Translocation) 01/2022
1	Papillary Thyroid Cancer 01/2021
1	Breast Neoplasms (Breast Cancer) 12/2020
1	Cicatrix (Scar) 01/2020
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2017
1	Poisoning 01/2016
1	Carcinogenesis 08/2015
1	Colitis-Associated Neoplasms 08/2015
1	Inflammation (Inflammations) 08/2015
1	Melanoma (Melanoma, Malignant) 08/2015
1	Colorectal Neoplasms (Colorectal Cancer) 08/2015
1	Chromosomal Instability (Chromosome Stability) 10/2014
1	Hypersensitivity (Allergy) 08/2009
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 08/2009
1	Werner Syndrome (Werner's Syndrome) 08/2002

Drug/Important Bio-Agent (IBA)

11	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 09/2004
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2002
3	DNA Polymerase thetaIBA 01/2020 - 10/2014
2	DNA polymerase muIBA 05/2008 - 10/2007
1	IodineIBA 01/2021
1	Cruciform DNA (Holliday Junctions)IBA 01/2021
1	ChromatinIBA 01/2021
1	Holliday Junction ResolvasesIBA 01/2021
1	Single-Stranded DNA (DNA, Single Stranded)IBA 01/2021
1	RibonucleotidesIBA 01/2018
1	Biological ProductsIBA 01/2017
1	Protein Kinases (Protein Kinase)IBA 01/2017
1	tyrosyl-DNA phosphodiesteraseIBA 01/2016
1	Biomarkers (Surrogate Marker)IBA 01/2016
1	PoisonsIBA 01/2016
1	AzoxymethaneIBA 08/2015
1	Dextrans (Dextran)FDA Link 08/2015
1	Interleukin-18 (Interleukin 18)IBA 08/2015
1	InflammasomesIBA 08/2015
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 08/2015
1	Type II DNA Topoisomerases (Topoisomerase II)IBA 12/2012
1	trioctyl phosphine oxide (TOPO)IBA 12/2012
1	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 11/2009
1	Hydroxyurea (Hydrea)FDA LinkGeneric 11/2009
1	Small Interfering RNA (siRNA)IBA 08/2009
1	CalicheamicinsIBA 08/2009
1	SolutionsIBA 10/2007
1	DNA-Activated Protein KinaseIBA 09/2004
1	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 09/2004
1	RecQ HelicasesIBA 08/2002
1	Exonucleases (3' 5' Exonuclease)IBA 08/2002

Therapy/Procedure

3	Ligation 01/2017 - 12/2012
1	Nuclear Power Plants 01/2021
1	Therapeutics 12/2020
1	Precision Medicine 01/2016